
The One You Want for One-And-Done Monthly Protection
From the maker of the #1 vet-recommended heartworm disease preventive,1 HEARTGARD® Plus (ivermectin/pyrantel), NexGard® PLUS (afoxolaner, moxidectin, and pyrantel chewable tablets) gives you the power to protect your dog from fleas and ticks, prevent heartworm disease, and treat and control roundworms and hookworms. Delicious, beef-flavored NexGard PLUS soft chews are available by prescription only—talk to your vet to see if they’re right for your dog. See How NexGard PLUS Chews Compare to the Competition.
Protection That's Easy to Give
NexGard PLUS chews are designed to be easy to give to dogs. They’re beef-flavored, chewable, and soft—no pill pockets, peanut butter, or cheese needed. Dogs need parasite protection year-round, and NexGard PLUS chews are designed so that giving your dog their monthly dose is a delight—and never a chore—month after month.
The One-And-Done Monthly Chew You Want
NexGard PLUS chews kill adult fleas, kill ticks, prevent heartworm disease, and treat and control 3 species of hookworms and 2 species of roundworms. Given every month, NexGard PLUS chews give you the power to protect your dog year-round.
Safe for Puppies
NexGard PLUS chews are safe to start protecting puppies as young as 8 weeks, weighing 4 pounds or more. Every delicious, beef-flavored soft chew provides monthly One-And-Done protection for dogs young and old.
Click “Redeem With Receipt” if you have already purchased from your vet, or “Email Offer Code” to save your code for later.
NexGard PLUS chews are approved for use in dogs 8 weeks of age or older weighing 4 lbs or more.
Compare to Other Products
NexGard® PLUS | SIMPARICA TRIO®2 | |
---|---|---|
Beef-Flavored Soft Chew |
applicable | |
From the maker of the #1 Heartworm Disease Preventive1 |
applicable | |
Kills Adult Fleas Before They Can Lay Eggs |
applicable | applicable |
Kills Ticks | applicable | applicable |
Prevents Heartworm Disease | applicable | applicable |
Treats & Controls 3 Hookworm Species |
applicable | 2 species |
Treats & Controls 2 Roundworm Species |
applicable | applicable |
Approved for Dogs and Puppies as Young as 8 Weeks |
Weighing 4 lbs or more | Weighing 2.8 lbs or more |
Find Protection for Your Dog or Cat
Learn more about our products. Your vet can help you determine the right protection for your pet.

NexGard PLUS Chews: One-And-Done Monthly Protection for Dogs
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KILLS fleas & ticks
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PREVENTS heartworm disease
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TREATS and controls roundworms and hookworms
IMPORTANT SAFETY INFORMATION
NexGard® PLUS (afoxolaner, moxidectin, and pyrantel chewable tablets) is safe for puppies at 8 weeks, weighing 4 pounds or more. The most frequently reported adverse reactions include diarrhea, vomiting, lethargy, and itching. Use with caution in dogs with a history of seizures or neurologic disorders. Dogs should be tested for existing heartworm infection prior to starting a preventive. For more information, click here for full prescribing information.

NexGard COMBO Topical Solution: Monthly Protection for Cats
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KILLS fleas & ticks
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PREVENTS heartworm disease
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TREATS and controls tapeworms, roundworms, and hookworms
IMPORTANT SAFETY INFORMATION
NexGard® COMBO (esafoxolaner, eprinomectin, and praziquantel topical solution) is for topical use only in cats. Use with caution in cats with a history of seizures or neurologic disorders. The most frequently reported adverse reactions include vomiting, application site reactions, and anorexia. If ingested, hypersalivation may occur. Avoid direct contact with application site until visibly dry. For more information, click here for full prescribing information.

NexGard Chews: Monthly Flea & Tick Protection for Dogs
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KILLS fleas & ticks
-
PREVENTS Lyme disease infections by killing black-legged ticks
IMPORTANT SAFETY INFORMATION
NexGard® (afoxolaner) is for use in dogs only and is safe for dogs 8 weeks or older and weighing 4 pounds or more. The most frequently reported adverse reactions include vomiting, itching, lethargy, diarrhea, and lack of appetite. The safe use of NexGard in pregnant, breeding, or lactating dogs has not been evaluated. Use with caution in dogs with a history of seizures or neurologic disorders. For more information, click here for full prescribing information.

NexGard PLUS Chews: One-And-Done Monthly Protection for Dogs
-
KILLS fleas & ticks
-
PREVENTS heartworm disease
-
TREATS and controls roundworms and hookworms
IMPORTANT SAFETY INFORMATION
NexGard® PLUS (afoxolaner, moxidectin, and pyrantel chewable tablets) is safe for puppies at 8 weeks, weighing 4 pounds or more. The most frequently reported adverse reactions include diarrhea, vomiting, lethargy, and itching. Use with caution in dogs with a history of seizures or neurologic disorders. Dogs should be tested for existing heartworm infection prior to starting a preventive. For more information, click here for full prescribing information.

NexGard COMBO Topical Solution: Monthly Protection for Cats
-
KILLS fleas & ticks
-
PREVENTS heartworm disease
-
TREATS and controls tapeworms, roundworms, and hookworms
IMPORTANT SAFETY INFORMATION
NexGard® COMBO (esafoxolaner, eprinomectin, and praziquantel topical solution) is for topical use only in cats. Use with caution in cats with a history of seizures or neurologic disorders. The most frequently reported adverse reactions include vomiting, application site reactions, and anorexia. If ingested, hypersalivation may occur. Avoid direct contact with application site until visibly dry. For more information, click here for full prescribing information.

NexGard Chews: Monthly Flea & Tick Protection for Dogs
-
KILLS fleas & ticks
-
PREVENTS Lyme disease infections by killing black-legged ticks
IMPORTANT SAFETY INFORMATION
NexGard® (afoxolaner) is for use in dogs only and is safe for dogs 8 weeks or older and weighing 4 pounds or more. The most frequently reported adverse reactions include vomiting, itching, lethargy, diarrhea, and lack of appetite. The safe use of NexGard in pregnant, breeding, or lactating dogs has not been evaluated. Use with caution in dogs with a history of seizures or neurologic disorders. For more information, click here for full prescribing information.

NexGard® Brand Products
When it comes to parasite protection for the dogs and cats in your home, NexGard® Brand Products have them covered. For dogs, there’s NexGard PLUS chews or NexGard chews. And for cats, there’s NexGard COMBO topical solution. Ask your vet to learn more about each of these products.
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IMPORTANT SAFETY INFORMATION:
NexGard® PLUS (afoxolaner, moxidectin, and pyrantel chewable tablets) is safe for puppies at 8 weeks, weighing 4 pounds or more. The most frequently reported adverse reactions include diarrhea, vomiting, lethargy, and itching. Use with caution in dogs with a history of seizures or neurologic disorders. Dogs should be tested for existing heartworm infection prior to starting a preventive. For more information, click here for full prescribing information.
NexGard® COMBO (esafoxolaner, eprinomectin, and praziquantel topical solution) is for topical use only in cats. Safe for use in cats and kittens 8 weeks of age or older, weighing 1.8 pounds or more. Use with caution in cats with a history of seizures or neurologic disorders. The most frequently reported adverse reactions include vomiting, application site reactions, lethargy, and anorexia. If ingested, hypersalivation may occur. Avoid direct contact with application site until visibly dry. For more information, click here for full prescribing information.
NexGard® (afoxolaner) is for use in dogs only. Safe for use in puppies 8 weeks of age or older, weighing 4 pounds or more. The most frequently reported adverse reactions include vomiting, itching, lethargy, diarrhea, and lack of appetite. The safe use of NexGard in pregnant, breeding, or lactating dogs has not been evaluated. Use with caution in dogs with a history of seizures or neurologic disorders. For more information, click here for full prescribing information.
Following the use of HEARTGARD® Plus (ivermectin/pyrantel), digestive and neurologic side effects have been reported. Safe for puppies 6 weeks of age or older. For more information, please click here for full prescribing information.