Proven, Next-Level Monthly Protection
One-and-Done Monthly.
An Easy Switch.
Try out NexGard® PLUS (afoxolaner, moxidectin, and pyrantel chewable tablets) and see the difference with our vet-recommended, beef-flavored chew dogs love.
*For dogs demonstrating a preference, they preferred NexGard PLUS chews over the competition.
Protection against:
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Fleas
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Ticks
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Heartworm disease
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Roundworms
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Hookworms
SEE THE DIFFERENCE
How Does It Compare?
See how NexGard® PLUS (afoxolaner, moxidectin, and pyrantel chewable tablets) compares to
NexGard® (afoxolaner) and other brands and why it’s the vet-recommended, delicious chew for dogs.
NexGard PLUS vs. NexGard Chews
NexGard PLUS vs. NexGard Chews
Prevents heartworm disease | Treats & controls roundworms and hookworms | Kills | Kills | Same efficacy with or without food | Approved for dogs and puppies as young as 8 weeks | Prevents Lyme infections* | |
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* Prevents Lyme infections as a direct result of killing black-legged ticks
NexGard PLUS vs. Simparica Trio®
NexGard PLUS vs. Simparica Trio®
Tasty beef-flavored chew Preferred by dogs*Φ | Treats & controls 3 species of hookworms | Kills | Kill 6 types | Prevents heartworm disease | Treats & | Same efficacy with or | Prevents | |
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SIMPARICA TRIO®β | 2 |  | | | | | |
* In a study, for dogs that demonstrated a preference, they preferred NexGard® PLUS chews over SIMPARICA TRIO®.
** As a direct result of killing black-legged ticks.
NexGard PLUS vs. Bravecto®
NexGard PLUS vs. Bravecto®
Prevents heartworm disease | Same efficacy with or without food | Treats and controls hookworms and roundworms | Prevents Lyme infections* | Kills | Approved for dogs and puppies as young as 8 weeks, weighing 4lbs or more | Tasty beef-flavored chew | Kills | |
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| BRAVECTO®ψ |
| Kills 5 types of ticks Lone Star Tick for 8 weeks only. | 6+ months, weighing 4.4 lbs or more | Pork-flavored chew |  |
* As a direct result of killing black-legged ticks.
NexGard PLUS vs. Credelio Quattro®
NexGard PLUS vs. Credelio Quattro®
Can be | Treats & | Kills 6 types | Kills | Prevents | Prevents | Treats and | |
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| CREDELIO QUATTRO®Σ | 2 | Kills 5 types |  | | | |
* As a direct result of killing black-legged ticks.
$25 rebate
When you buy 6 doses of NexGard PLUS chews from your vet, we’ll send you a $25 rebate on your purchase.* For NexGard PLUS chews, your dog needs a negative heartworm test and prescription from your vet. Offer expires July 31, 2026.
$65 rebate
When you buy 12 doses of NexGard PLUS chews from your vet, we’ll send you a $65 rebate on your purchase.* For NexGard PLUS chews, your dog needs a negative heartworm test and prescription from your vet. Offer expires July 31, 2026.
3 Steps To Get Protection
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Choose Your NexGard Brand Product
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Get a Prescription From Your Vet
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Purchase Through Your Vet or Online
- Data on file at Boehringer Ingelheim.
β. SIMPARICA TRIO® Prescribing Information
Φ. Data on file at Boehringer Ingelheim.
ψ. BRAVECTO® Prescribing Information
Σ. CREDELIO QUATTRO® Prescribing Information
Important Safety Information
NexGard® PLUS (afoxolaner, moxidectin, and pyrantel chewable tablets) is safe for puppies at 8 weeks, weighing 4 pounds or more. The most frequently reported adverse reactions include diarrhea, vomiting, lethargy, and itching. Use with caution in dogs with a history of seizures or neurologic disorders. Dogs should be tested for existing heartworm infection prior to starting a preventive. For more information, click here for full prescribing information.
NexGard® COMBO (esafoxolaner, eprinomectin, and praziquantel topical solution) is for topical use only in cats. Safe for use in cats and kittens 8 weeks of age or older, weighing 1.8 pounds or more. Use with caution in cats with a history of seizures or neurologic disorders. The most frequently reported adverse reactions include vomiting, application site reactions, lethargy, and anorexia. If ingested, hypersalivation may occur. Avoid direct contact with application site until visibly dry. For more information, click here for full prescribing information.
NexGard® (afoxolaner) is for use in dogs only. Safe for use in puppies 8 weeks of age or older, weighing 4 pounds or more. The most frequently reported adverse reactions include vomiting, itching, lethargy, diarrhea, and lack of appetite. The safe use of NexGard in pregnant, breeding, or lactating dogs has not been evaluated. Use with caution in dogs with a history of seizures or neurologic disorders. For more information, click here for full prescribing information.