FAQS

NexGard® (afoxolaner) chews

Safety

Are NexGard chews safe?

Are NexGard chews safe for pregnant dogs? 

Are NexGard chews safe for nursing dogs? 

Can NexGard chews be used with other medications?

Can you give NexGard chews and HEARTGARD® Plus (ivermectin/pyrantel) at the same time?

What is the best number to call regarding NexGard chews questions?

Administration

How often can I give NexGard chews to my dog? 

How do I give NexGard  chews to my dog?

Is there a weight or age requirement to give my dog NexGard chews?

Can I start dosing my dog with NexGard chews at any time during the year?

Do NexGard chews for dogs need to be given with food?

What do I do if my dog spits up their NexGard chew?

What sizes and options are NexGard chews available in?

Can I give my dog NexGard chews early?

What happens if you miss a month of NexGard chews dosing?

Can NexGard chews be crushed?

What happens if I accidentally give my dog two NexGard chews?

General

What are NexGard chews for dogs?

What do NexGard chews protect against?

How do NexGard chews work?

How long does it take for NexGard chews to kill fleas? 

How long does a dose in NexGard chews last?

How long does it take for NexGard chews to work?

How do NexGard chews kill fleas?

How do I know if NexGard chews are working?

Are NexGard chews recommended for all dogs?

Can I purchase NexGard chews without a vet prescription?

What's the difference between NexGard chews and HEARTGARD Plus chews?

What's the difference between NexGard chews and Frontline® Brand Products for dogs?

What are the signs of fleas on dogs?

Can my dog’s fleas go away on their own?

Do NexGard chews protect dogs from Lyme infections?

Why does my dog still have fleas after using NexGard chews?

Will NexGard chews kill existing fleas?

What happens if fleas go untreated on dogs?

What do I do if my dog is already on NexGard chews and has a tick?

Can dogs get sick from ticks?

What are the signs of ticks on dogs?

  1. Dryden M. Biology of fleas of dogs and cats. Compend Contin Educ Vet. 1993(4):569-579.
  2. Lyme Disease. Companion Animal Parasite Council. April 28, 2025. Accessed April 21, 2025. https://capcvet.org/guidelines/lyme-disease

Important Safety Information

NexGard® (afoxolaner) is for use in dogs only. Safe for use in puppies 8 weeks of age or older, weighing 4 pounds or more. The most frequently reported adverse reactions include vomiting, itching, lethargy, diarrhea, and lack of appetite. The safe use of NexGard in pregnant, breeding, or lactating dogs has not been evaluated. Use with caution in dogs with a history of seizures or neurologic disordersFor more information, click here for full prescribing information.