NexGard
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Proven, Next-Level Protection

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One-and-Done Monthly Protection

NexGard® COMBO (esafoxolaner, eprinomectin, and praziquantel topical solution) is the one-and-done monthly topical solution that comes with an award-winning applicator, making it easy to use. 

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NG Combo 3 Pack for Large Cats - SKU 608336

Protection against:

  • Fleas

    Fleas

  • Heartworm

    Heartworm disease

  • Hookworms

    Hookworms

  • Ticks

    Ticks

  • Roundworm

    Roundworms

  • Tapeworms

    Tapeworms

Important Safety Information

PROTECTION REMINDER FOR YOUR PET

Never miss a dose with monthly reminders. 

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Offers For Your Cat

$20 rebate

When you buy 6 doses of NexGard COMBO topical solution from your vet, we’ll send you a $20 rebate on your purchase.* Offer expires July 31, 2026.

NG_CMBO_6_Front_LG
Email Rebate Redeem with receipt

$50 rebate

When you buy 12 doses of NexGard COMBO topical solution from your vet, we’ll send you a $50 rebate on your purchase.* Offer expires July 31, 2026.

NGCOMBO Double pack
Email Rebate Redeem with receipt
Nexgard Combo Packshot for the review section

NexGard® COMBO

Have you used NexGard® COMBO on your cat? Tell us what you think.

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3 Steps To Get Protection

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  • Choose Your NexGard Brand Product

  • Get a Prescription From Your Vet

  • Purchase Through Your Vet or Online

Important Safety Information

NexGard® COMBO (esafoxolaner, eprinomectin, and praziquantel topical solution) is for topical use only in cats. Safe for use in cats and kittens 8 weeks of age or older, weighing 1.8 pounds or more. Use with caution in cats with a history of seizures or neurologic disorders. The most frequently reported adverse reactions include vomiting, application site reactions, lethargy, and anorexia. If ingested, hypersalivation may occur. Avoid direct contact with application site until visibly dry. For more information, click here for full prescribing information.