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Proven, Next-Level Protection 

One-and-Done Monthly. 
Year-Round Protection. 

NexGard® PLUS (afoxolaner, moxidectin, and pyrantel chewable tablets) is the vet-recommended, broad spectrum protection dogs prefer.*1 Keep up with monthly doses for year-round protection.



*For dogs demonstrating a preference, they preferred NexGard PLUS chews over the competition.

NG Plus 1 Pack for Large Dogs

Protection against:

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    Fleas icon

    Fleas

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    Ticks icon

    Ticks

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    Heartworm Disease Icon

    Heartworm disease

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    Roundworms Icon

    Roundworms

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    Hookworms Icon

    Hookworms

Protection REMINDERS for your pet

Never miss a dose with monthly reminders.

Offers For Your Dog

$25 rebate

When you buy 6 doses of NexGard PLUS chews from your vet, we’ll send you a $25 rebate on your purchase.* For NexGard PLUS chews, your dog needs a negative heartworm test and prescription from your vet. Offer expires July 31, 2026.

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$65 rebate

When you buy 12 doses of NexGard PLUS chews from your vet, we’ll send you a $65 rebate on your purchase.* For NexGard PLUS chews, your dog needs a negative heartworm test and prescription from your vet. Offer expires July 31, 2026.

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NGP_12-dose_rebate

Why protect?

Stay Informed About
Parasite Risks

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Roundworm
90% of Puppies

More than 90% of puppies under 3 months of age are infected with roundworms.1

90% of Puppies

More than 90% of puppies under 3 months of age are infected with roundworms.1

Thankfully, NexGard PLUS Chews are safe for puppies 8 weeks or older, weighing 4 pounds or more.

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Tick
12 Months

Ticks are active 12 months a year.2
 

12 Months

Ticks are active 12 months a year.2

Tick populations drop only 20% in the winter. Protect your pet with NexGard PLUS Chews. Contact your vet to help you select the right dosage.

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Flea
3,000 Eggs

A flea can lay up to 3000 eggs in its lifetime and can live up to 100 days on your pet.3

3,000 Eggs

A flea can lay up to 3000 eggs in its lifetime and can live up to 100 days on your pet.3

NexGard PLUS can help you prevent flea infestation with a one-and-done monthly chew.

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Heartworm
1.2 Million Dogs

1.2 million dogs in the US are estimated to have heartworm disease.4

1.2 Million Dogs

1.2 million dogs in the US are estimated to have heartworm disease.4

Ask your vet about how you can protect your dog with NexGard PLUS monthly chews.

Nexgard plus packshot for the review section

NEXGARD® PLUS

Have you given your dog NexGard® PLUS? Tell us what you think.

3 Steps To Get Protection

  1. Schantz PM. Zoonotic ascarids and hookworms: the role for veterinarians in preventing human disease. Accessed February 24, 2025. 
  2. Grant AN, Lineberry MW, Sundstrom KD, et al. Geographic Distribution and Seasonality of Brown Dog Tick Lineages in the United States. J Med Entomol. 2023;60:102–111.
  3. News, PVM. 2022. “Indiana Media Outlet Turns to PVM’s Dr. Paulo Gomes for Advice for Pet Owners about Fleas.” College of Veterinary Medicine. July 22, 2022. https://vet.purdue.edu/news/indiana-media-outlet-turns-to-pvms-dr-paulo-gomes-for-advice-for-pet-owners-about-fleas.php.
  4. Heartworm incidence climbs despite preventive efforts. American Veterinary Medical Association. Published October 8, 2025. https://www.avma.org/news/heartworm-incidence-climbs-despite-preventive-efforts

Important Safety Information

NexGard® PLUS (afoxolaner, moxidectin, and pyrantel chewable tablets) is safe for puppies at 8 weeks, weighing 4 pounds or more. The most frequently reported adverse reactions include diarrhea, vomiting, lethargy, and itching. Use with caution in dogs with a history of seizures or neurologic disorders. Dogs should be tested for existing heartworm infection prior to starting a preventive. For more information, click here for full prescribing information.