NexGard
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 Next-Level Protection For Next-Level Dog Lovers

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Proven, One-and-Done Monthly Puppy Protection

NexGard® PLUS (afoxolaner, moxidectin, and pyrantel chewable tablets) is the vet-recommended, broad spectrum protection dogs prefer.*1 Keep up with monthly doses for year-round protection.  

*For dogs demonstrating a preference, they preferred NexGard PLUS chews over the competition.

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NG Plus 1 Pack for Large Dogs

Protection against:

  • Fleas icon

    Fleas

  • Ticks icon

    Ticks

  • Heartworm Disease Icon

    Heartworm disease

  • Roundworms Icon

    Roundworms

  • Hookworms Icon

    Hookworms

Important Safety Information
Offer For Your Dog

Why protect?

Stay Informed About
Parasite Risks

Roundworm
90% of Puppies

More than 90% of puppies under 3 months of age are infected with roundworms.1

90% of Puppies

More than 90% of puppies under 3 months of age are infected with roundworms.1

Thankfully, NexGard PLUS Chews are safe for puppies 8 weeks or older, weighing 4 pounds or more.

Schantz PM. Zoonotic Ascarids and Hookworms
Tick
12 Months

Ticks are active 12 months a year.2
 

12 Months

Ticks are active 12 months a year.2

Tick populations drop only 20% in the winter. Protect your pet with NexGard PLUS Chews. Contact your vet to help you select the right dosage.

Grant AN, et. al., Geographic Distribution and Seasonality of Brown Dog Tick
Flea
3,000 Eggs

A flea can lay up to 3000 eggs in its lifetime and can live up to 100 days on your pet.3

3,000 Eggs

A flea can lay up to 3000 eggs in its lifetime and can live up to 100 days on your pet.3

NexGard PLUS can help you prevent flea infestation with a one-and-done monthly chew.

Purdue University
Heartworm
1.2 Million Dogs

1.2 million dogs in the US are estimated to have heartworm disease.4

1.2 Million Dogs

1.2 million dogs in the US are estimated to have heartworm disease.4

Ask your vet about how you can protect your dog with NexGard PLUS monthly chews.

American Veterinary Medical Association

SEE THE DIFFERENCE

Compare NexGard PLUS to other brands

NexGard PLUS vs. NexGard Chews

/
 

 

Prevents heartworm disease 

 

Treats & controls roundworms and hookworms

 

Kills 
fleas

 

Kills 
ticks

 

Same efficacy with or without food

 

Approved 
for dogs and puppies as young as 8 weeks
and weighing 4 lbs or more

 

Prevents Lyme infections*

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* Prevents Lyme infections as a direct result of killing black-legged ticks

NexGard PLUS vs. Simparica Trio®

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Tasty beef-flavored chew
Preferred by dogs*5

Treats & controls 3 species of hookworms

Kills 
fleas

Kills 
ticks
including longhorned ticks

Prevents heartworm disease 

Treats &
controls roundworms

Same efficacy with or
without food

Prevents
Lyme infections**

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SIMPARICA TRIOβ 

2
species

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* In a study, for dogs that demonstrated a preference, they preferred NexGard PLUS chews over SIMPARICA TRIO®.
** As a direct result of killing black-legged ticks.

NexGard PLUS vs. Bravecto

/
 

Prevents heartworm disease 

Same efficacy with or without food

Treats and controls hookworms and roundworms

Prevents Lyme infections*

Approved 
for dogs and puppies as young as 8 weeks, weighing 4lbs or more

Tasty beef-flavored chew

Kills 
fleas

Kills 
ticks
including longhorned ticks

t

 

t

 

ttt

t

Weighing 4 lbs or more

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BRAVECTOψ    6+ months, weighing 4.4 lbs or morePork-flavored chew

* As a direct result of killing black-legged ticks.

NexGard PLUS vs. Credelio Quattro®

/
 

Can be
conveniently given with or without food

Prevents
Lyme infections*

Kills 
ticks

Kills 
fleas

Prevents
heartworm disease 

Treats &
controls 3 species of hookworms

Treats and
controls roundworms

tttttttt
CREDELIO QUATTROΣ   

1
species

* As a direct result of killing black-legged ticks.

Protection Reminders for your pet

Never miss a dose with monthly reminders.

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3 Steps To Get Protection

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  • Choose Your NexGard Brand Product

  • Get a Prescription From Your Vet

  • Purchase Through Your Vet or Online

  1. Data on file at Boehringer Ingelheim.
  2. Schantz PM. Zoonotic ascarids and hookworms: the role for veterinarians in preventing human disease. Accessed February 24, 2025. 
  3. Grant AN, Lineberry MW, Sundstrom KD, et al. Geographic Distribution and Seasonality of Brown Dog Tick Lineages in the United States. J Med Entomol. 2023;60:102–111.
  4. Dryden, M.W., 1993. Biology of fleas of dogs and cats. Comp. Cont. Educ. Pract. Vet, 15(4), pp.569-579.
  5. Heartworm incidence climbs despite preventive efforts. American Veterinary Medical Association. Published October 8, 2025. https://www.avma.org/news/heartworm-incidence-climbs-despite-preventive-efforts

    β. SIMPARICA TRIO® Prescribing Information 
    Φ. Data on file at Boehringer Ingelheim. 
    ψ. BRAVECTO® Prescribing Information 
    Σ. CREDELIO QUATTRO® Prescribing Information

Important Safety Information

NexGard® PLUS (afoxolaner, moxidectin, and pyrantel chewable tablets) is safe for puppies at 8 weeks, weighing 4 pounds or more. The most frequently reported adverse reactions include diarrhea, vomiting, lethargy, and itching. Use with caution in dogs with a history of seizures or neurologic disorders. Dogs should be tested for existing heartworm infection prior to starting a preventive. For more information, click here for full prescribing information.