NexGard COMBO topical solution has been extensively studied in both laboratory studies and in real-world conditions in cats. The safety of NexGard COMBO topical solution has been demonstrated in cats, including in heartworm-positive cats,  as well as in kittens as young as 8 weeks of age, weighing 1.8 pounds or more. The most frequently reported adverse reactions include vomiting, application site reactions, lethargy, and anorexia.

The most frequently reported reactions include vomiting, application site reactions and anorexia. If ingested, hypersalivation may occur. Use with caution in cats with a history of seizures or neurologic disorders.

No. NexGard COMBO topical solution is for topical use in cats only. For protection for your dog, check out NexGard® PLUS (afoxolaner, moxidectin, and pyrantel chewable tablets). Use with caution in dogs with a history of seizures or neurologic disorders. For the full prescribing information, click here. 

The safety of NexGard COMBO topical solution has not been fully evaluated in pregnant, breeding, or lactating cats.

Use of NexGard COMBO topical solution in conjunction with other treatments (eg, vaccines, antibiotics, analgesics) had no effect on safety. For any specific questions that you have related to the use of NexGard COMBO topical solution with other medications, speak to your veterinarian.

If your cat licks NexGard COMBO, they may experience a brief period of hypersalivation. This is usually short-lived and doesn’t have any long-term effects.

For any specific product questions, please call Boehringer Ingelheim Animal Health at 1-888-637-4251.

NexGard COMBO topical solution is safe for use in cats and kittens 8 weeks of age or older, weighing 1.8 lbs or more.

NexGard COMBO topical solution protects against fleas and ticks fast for a full month. Each monthly dose will treat roundworm, hookworm, and tapeworm infections, and prevent heartworm disease by killing larval stage heartworms before they can mature to adults. NexGard COMBO topical solution should be administered once a month, year-round to ensure that your cat is protected from the risks posed by these parasites.

Yes. Treatment with NexGard COMBO topical solution can be started any time during the year. For heartworm disease prevention, apply once monthly for at least 3 months after last exposure to mosquitoes.

NexGard COMBO topical solution should be applied directly to the s kin by parting the cat’s hair on the midline of the neck between the base of the skull and the shoulder blades to minimize the possibility of the cat grooming/licking the product off.

NexGard COMBO topical solution is available in packs containing either 3 or 6 topical doses and comes in two different sizes:

• 1.8-5.5 lbs
• 5.6-16.5 lbs

NexGard COMBO protects against fleas and ticks, prevents heartworm disease, and treats and controls roundworms, hookworms, and tapeworms.

NexGard COMBO kills fleas within 48 hours of infestation and ticks within 72 hours of infestation.

Yes. Even indoor-only cats can become exposed to external and internal parasites. Fleas and ticks can be brought into the home by other pets or they can even hitchhike in on people. An infested pet will spread flea eggs throughout the house. These developing stages will survive in the areas that the infested pet frequents (carpet, cracks in hardwood floors, pet bedding, etc). Other animals, such as rodents, can be infected with intestinal parasites that can infect an indoor cat. Mosquitoes can transmit heartworms, which can cause heartworm disease even in indoor-only cats.

You are likely seeing NEW fleas on your pet, which are jumping on your cat as it moves through infested areas. These fleas will be killed quickly by NexGard COMBO topical solution before they can reproduce. Depending on the severity of an already existing infestation as well as environmental conditions, you may continue to see new fleas jumping on your pet for 3 months or more. To prevent new infestations, continue to consistently give NexGard COMBO topical solution monthly and year-round.

Cats get infected with heartworms by being bitten by an infected mosquito. One bite is all it takes.¹ After infection, the heartworms become adults and cause heartworm disease that can have fatal effects.

The most common way to confirm an intestinal parasite infection is with a fecal test from your vet to detect the presence of parasite eggs. Prompt treatment of cats can help reduce further damage as well as mitigate the possibility of the worms spreading. Common signs include diarrhea, vomiting, weight loss as a general sign, poor coat appearance, swollen belly, lethargy, dehydration, anemia, or blood in stool. Check their litter box often, as a general sign of tapeworms is rice-like proglottids that show up in their feces.

Cats get infected with heartworms by being bitten by an infected mosquito. One bite is all it takes.¹ After infection, the heartworms become adults and cause heartworm disease that can have fatal effects.

Although most cats won't show signs once infected, cats may develop respiratory signs (including coughing or wheezing) that can be confused with other illnesses, such as allergies, asthma, or bronchitis. Other signs include difficulty breathing, vomiting, loss of appetite, and weight loss. Unfortunately, the first signs in some cats can be severe, and include collapse, seizures, and sudden death. Infection causes lasting damage in cats, and can result in lung disease, heart failure, and even death.

Yes, heartworm disease prevention is an essential part of a cat’s preventive healthcare regimen. While infection rates of heartworm disease are lower in cats than in dogs, cats are at risk of this devastating disease. The American Heartworm Society and Companion Animal Parasite Council recommend that all cats in the US receive a heartworm disease preventive year-round.

Some internal parasites that can infect cats include roundworms, hookworms, and tapeworms.

External parasites in cats can include fleas and ticks.

Fleas can cause itchy, painful skin conditions on your cat. Signs of fleas include scratching or biting at the skin, hair loss, scabs, and irritation.

If fleas go untreated, they can quickly multiply to cause an infestation. A single adult flea can lay up to 50 eggs per day, which means that a small number of fleas can grow into the thousands.² Fleas feed on a host’s blood, so they can also cause anemia, which can be severe in kittens or smaller animals. Fleas can also transmit other pathogens or parasites, such as tapeworms. An infested cat will scatter flea eggs throughout their home environment, and fleas can bite other animals, including humans.

Ticks can be hard to spot on cats. Since they bite the skin—underneath your cat’s fur—it can be difficult to locate them. They also may bite hard-to-reach areas, such as under the collar at the neck or beneath the armpits. Your cat may scratch at or gnaw on tick bite locations.